There are interesting things to see in so many places that it is hard to pick the
best, when this means leaving out so many places most of the guidebooks don't
seem to know about. Here is just a small selection. We've attempted also to collect information which is kept in a folder for guests in the villa covering these and many other places of interest. (Click on the images below to enlarge.)
Ostuni - the White City
Ostuni by night
Oria, the Walled Town 
Lecce, the Roman and Baroque City
Alberobello - The Trulli Capital 
Matera, in Basilicata, and its Sassi
Monopoli, with its old town and port 
Picturesque port of Villanova
PLUS:
Grottaglie - the must-see town for people who love ceramics, from rustic to exquisite hand-made pieces, as made under these castle walls since Medieval times.
This Grottaglie Ceramics web site is in Italian but shows the range.
Castellana Caves - kms of caverns, long and short tours, within 30 mins' drive
Visit the Grotte web site
Egnazia, the Archaeological site
just 30 minutes drive from the villa - see the website
Martina Franca, the highest town of the Murgia hills - well worth a trip. The Comune of Martina Franca provides a web site in English.
Torre Guaceto, the internationally protected Marine and Nature Reserve.
There's also a sailing centre, and a centre for kite surfing nearby. In the summer there are organised tours and bike rides. We recommend visiting the Visitors'
Centre in Serranova first.
Visit the Reserve's website
Fasano Zoo Safari, includes Puglia in Miniature, a must with children. Only open
the Zoo Safari web site if you like loud music. And it's in Italian.
Plus many more sights and places of interest within an hour's drive.